Work Package 2

Observational study about the effects of proportional sedation

Lead beneficiary:
Radboud UMC, Nijmegen, the Netherlands

Radboud University Medical School logo


The  objective  of  this work package is to perform an observational study into  the effect of palliative sedation in five palliative care centres in Europe.

  • Drafting a joint research protocol
  • Submission and approval of ethical committees
  • Drafting a case report form and set-up of clinical research database
  • Training of local clinical and research staff to prepare for the research study
  • Inclusion of patients, informed consent, and measurement activities
  • Analysis of results and draft publication

Associate Professor Jeroen Haseelaar is the Work Package 2 lead and talks about the aims and objectives of this team:

Work Package 2 Team

“As Work Package 2 Lead and PI for the project I will focus on improved ways of assessing and managing refractory symptoms and the adequate use of palliative sedation, taking into account differences across Europe in both clinical and ethical aspects.”

Jeroen Hasselaar

Work Package 2 Lead

“Member of the PhD commission of PhD researchers.”

Kris Vissers


Annick is the Project Manager of the Palliative Sedation research project and takes care of the management of the project consortium, the management of the periodic and final reporting to the EU and the management of legal issues. From 2011-2015 she was the Project Manager of an FP7 EU research project on implementing indicators to improve the organization of palliative care (IMPACT).

Annick Stijns

Project Manager

Maaike works as a junior researcher on work package 2. In this WP a clinical observational study will be performed in 5 countries of the consortium: Belgium, Germany, Italy, Spain and the Netherlands. Products to be delivered from this WP are: the research protocol, case-report forms, reports and publication.

Maaike van der Lee-Rijpstra

PhD Candidate

Other Work Package Partners

We are grateful to the following project partners who worked with us in this work package:

University of Navarra (WP1)
UZ Leuven (WP3)
University Hospital Bonn (WP6)
La Maddalena S.p.A. (MCC)